Technical Assistant I - Jain Lab#00261

The Jain lab studies the role of RNA aggregation in human health and disease. We are investigating how defective RNA processing may contribute to certain genetic neurological diseases such as Huntington disease and amyotrophic lateral sclerosis. We use a variety of biophysical and biochemical approaches to examine aberrations in RNA processing at a molecular and cellular level.

We are looking for a motivated individual to join our growing team in Technical Assistant I position. The technical assistant will conduct experiments to characterize the effects of RNA aggregation in cell culture models. 

Classification:     Exempt: Research Staff

Reports to:           Principal Investigator or other supervisory lab personnel

OVERALL RESPONSIBILITY

Designs and performs bench level experiments and independent research projects to support scientific research objectives of a lab or group. Analyzes experimental data, addresses methodological problems in experimental protocols and results, and reports data to supervisor. Conducts laboratory tasks and organization to ensure the smooth operation of the group. Uses discretion in prioritizing and organizing workflow and in optimizing methodologies and results.

CHARACTERISTIC DUTIES

  • Cloning and engineering of DNA constructs.
  • Mammalian cell culture and transgene expression.
  • Biochemical assays, gel electrophoresis, immunoblot.
  • Protein expression and purification.
  • Light microscopy, and imaging data analysis.
  • Independently operates lab equipment and prepares and orders necessary supply stocks. May work with vendors to address equipment, reagent, or supply issues.
  • Documents, compiles, and assists in interpreting experimental data. Reports data to supervisor in oral and written reports.
  • May assist with determining the order of research processes that best support essential project goals.
  • May consult scientific literature as needed.
  • Other tasks as required or assigned.

Qualifications:

  • Bachelor's degree in bioengineering, biology or a field directly related to the work.
  • Must have 1+ years of experience in a biomedical research laboratory.
  • Proficiency in basic lab techniques and principles of molecular/cell biology.
  • Excellent record keeping and organization skills.
  • Experience in microscopy a plus.
  • Excellent written and oral communication skills, strong organizational skills required.

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