Technical Assistant I, Metabolomics Core#00293


TITLE:  Technical Assistant I
CLASSIFICATION: Exempt: Research Staff
REPORTS TO: Principal Investigator 

The Metabolite Profiling Core Facility is seeking an enthusiastic and motivated individual who is interested in supporting metabolism-based research projects in a variety of experimental models through the use of liquid-chromatography mass-spectrometry

Whitehead Institute for Biomedical Research is a leading, nonprofit research and educational institution that has defined the cutting edge of biomedical science, creating a legacy of research excellence and academic eminence since 1982. Wholly independent in its governance, finances and research programs, Whitehead shares a teaching affiliation with Massachusetts Institute of Technology (MIT), offering the intellectual, collegial and scientific benefits of a leading research university. Whitehead's Faculty Members and Fellows run pioneering programs in cancer research, immunology, developmental biology, stem cell research, regenerative medicine, genetics and genomics-programs with a record of success. 

We offer excellent benefits including a choice of health insurance options; a generous retirement plan; comprehensive dental, disability and life insurance coverage; competitive salary, substantial vacation and holiday time; and programs for tuition reimbursement, dependent care assistance, pre-tax spending accounts, and subsidized public transportation or parking. 

Provide high-quality and professional support to our liquid-chromatography mass-spectrometry platform by performing bench level experiments. Uses discretion in prioritizing and organizing workflow. Works as part of a team to ensure high-quality data acquisition in a state-of-the-art and fast-paced laboratory. 

  • Provide high-quality and professional support to cutting edge scientific research
  • Process and prepares samples for analysis by LCMS
  • Prepare laboratory buffers and clean laboratory glassware
  • Organize laboratory supplies and orders as necessary to maintain laboratory stocks
  • Perform weekly cleaning and calibration of LCMS instruments 
  • Perform data quality checks
  • Attend team meetings. May participate in scientific conferences and contribute to scientific journals.
  • Consult with literature and scientific staff to maintain professional expertise.
  • Other tasks as required or assigned.

  • BS/MS in biology/biochemistry/ chemistry, or a field directly related to the work. 
  • Proficient in basic molecular biology and biochemical techniques, including working with micropipettes and buffer making
  • Must possess excellent interpersonal skills and the desire to work in a service-orientated environment.
  • Exceptional organizational and critical thinking skills; accurate lab notebook practices and attention to detail are essential.
  • Experience in the use of Microsoft office (Excel, Word, PowerPoint)
  • Excellent written and oral communication skills. 
  • Knowledge of biochemical reactions (or you are prepared to learn this).
  • Ability to exercise judgment within defined practices and techniques.
  • Flexibility and willingness to learn new technologies 
  • Ability to learn quickly and work in a fast-paced environment

At least one year of experience working in a biomedical research laboratory.
Experience with chromatography (GC or LC) and mass spectrometry 
Interest in advanced data processing and analysis encouraged (use of Matlab, R, Python etc)
Experience in the use of lab-specific software (ChemDraw, GraphPad Prism).

Interested candidates should submit a resume to
Or mail to:
Whitehead Institute, Attn: Human Resources
455 Main St.
Cambridge, MA 02142

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