Metabolomics Core Facility Director#00428

Classification: Exempt: Research Staff

Reports to: Principal Investigator 

The Metabolite Profiling Core Facility is seeking an enthusiastic and motivated individual who is interested in supporting metabolism-based research projects in a variety of experimental models through the use of high-resolution, accurate-mass, liquid chromatography mass spectrometry. 


The successful candidate will oversee and further develop the operation of a state-of-the-art facility consisting of targeted and untargeted metabolomics and lipidomics platforms using high-resolution, accurate-mass, liquid chromatography mass spectrometry (LC/MS). They will collaborate with and advise scientists at Whitehead, the Koch Institute for Cancer Research, MIT, and external institutions on developing and applying LC/MS-based metabolomic/lipidomic experiments to advance their research. In this highly collaborative position, the individual will be responsible for consulting on experimental design, analyzing and interpreting metabolomic/lipidomic data, and developing new LC/MS-based assays as projects dictate. The successful candidate will also participate in grant writing and manuscript preparation, as well as acquisition of new equipment to expand and advance scientific applications. This position will also involve supervising two research assistants, who help with the day-to-day maintenance and operation of the facility, as well as data analysis and other duties as needed.


  • PhD in Biology, Biochemistry, Analytical Chemistry, or related field
  • At least 5 - 7 years research experience in a biological/ biomedical setting required
  • Exceptional understanding of quantitative methods in mass spectrometry and metabolomics, including instrument operation, sample preparation, and data analysis
  • Experience with lipidomics or a willingness/ability to learn
  • Strong communication skills and ability to collaborate with scientists to consult on experimental design, data analysis and interpretation
  • Strong troubleshooting and problem-solving skills
  • Working knowledge of Orbitrap systems and accompanying software a plus
  • An understanding of the use of stable isotopes in mass spectrometry experiments will be helpful
  • A broad knowledge of high-resolution, accurate-mass data analysis software a plus 
  • Supervisory experience helpful and ability to work as a team essential
*Relocation bonus available

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